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By C.E.R. Jones (Eds.)

ISBN-10: 0444415580

ISBN-13: 9780444415585

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Professor F. M. A. are engaged in a systematic study of steroid profile/structure relationships. Among the steroids, the cardenolides are of particular interest because of the prevailing high incidence of heart disease in most of the highly developed nations of the world. /ml vs. /ml). PGLC tech- niques offer a simple, direct method for differentiation of various cardenolides found in drug preparations. Assaying of serum digoxin by PGLC is also an attractive possibility. (Figure 3 ) . , non-genetic) factors have ranged from 40-90%.

Of particular interest are the peak amplitude ratios within the bracketed area. The results are essentially like those obtained previously [4]. ACKNOWLEDGEMENTS Thanks are due to Dr. A. for furnishing the can- Malignant Cell Differentiation 1. Swiss Mouse-Normal Cell,58/ig /liW^'^WW 2. 'ilij^V^^', 3. Mouse Lymphoblastic Leukemia, 80/jLg 4. Mouse Tumor (Sarcoma), 61 jug J! ' » M U M * ! , Figure 5. J See legend for Steroid Differentiation Plate 56 cer cells. S. A. for culturing the gram negative "water bacteria" as well as assisting in their analyses, and to J.

Derrick, Anal. C h e m . , 48(1976)368R. 3 F . W . McLafferty, R. Knutti, R. Venkataraghavan, P J . G. D a w k i n s , Anal. C h e m . , 47(1975)1503. 4 D . I . Carroll, I. N. D. Haegele, and E . C . Horning, Anal. C h e m . , 47(1975)2369. W. -K. W. H. A. Bryce, Chem. , (1967)1215. Wipf, P. Irving, M. McCamish, R. Venkataraghavan, and McLafferty, J. Am. Chem. S o c . , 95(1973)3369. Smith, C . H. Maurer, and U. Rapp, J. Am. Chem. 96 (1974)3482. 8 J . H . Beynon, D . F . G. C o o k s , Anal. C h e m .

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Analytical Pyrolysis by C.E.R. Jones (Eds.)

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